We’ve all suffered at one time or another from what is called a sinus infection. Our first reaction is usually to call our Doctor’s office to request an antibiotic to get rid of it. New guidelines from our infectious disease experts now state that most people who have a sinus infection should NOT be treated with antibiotics because the drugs are unlikely to help. Although sinus infections are the fifth-leading reason for antibiotic prescriptions, 90-98 percent of cases are caused by viruses, which are not affected by antibiotics. Prescribing antibiotics for a viral sinus infection does not change the course of the infection and instead can spur the development of.