The Centers For Disease Control and Prevention (CDC) report 5 million people worldwide die every year from smoking or the complications from smoking. The best way to quit smoking is never to start smoking or prevent yourself from ever starting. But if you are already a smoker, here are some tips and alternative ways to quit: Nicotine replacement therapy in the form of patches, gum, lozenges, nasal spray or the medications bupropion (wellbutrin) or varenicline (Chantix). Oral fixation replacement. Chew on things like gum, toothpicks, mints and lozenges. Look for sugar free ones to avoid excess calories. Hypnosis or hypnotherapy. You must be open to this method. Make sure you.